By Janet Kanters

Micropep Technologies has expanded the regulatory pathway for its lead peptide-based biofungicide, Promisin, with submissions in the United States and European Union, following earlier filings in Brazil and Paraguay.

The latest applications mark another step in the company’s commercialization strategy, extending regulatory reviews across North America, Europe and Latin America. While the Brazil and Paraguay submissions focus on soybean diseases, the U.S. and EU dossiers include fungal diseases affecting grapes and potatoes.

Promisin is the first product developed using Micropep’s Krisalix discovery platform. The peptide-based biofungicide is designed for both broad-acre and high-value crops and is intended to provide a new mode of action for managing fungal diseases while fitting into existing crop protection programs.

The regulatory submissions are supported by more than three years of development and more than 200 field trials conducted across North America, Europe and Latin America. According to the company, the trials demonstrated consistent disease control both as a stand-alone treatment and when used alongside existing crop protection programs.

“The completion of our U.S. and EU regulatory submissions represents a defining milestone for Micropep and validates years of scientific innovation and field development Promisin,” said Dr. Kevin Leiner, chief regulatory officer at Micropep. “We are excited to begin the regulatory review process and to work closely with authorities to bring Promisin, our first peptide-based biofungicide, to growers seeking innovative and sustainable crop protection solutions.”

Earlier submissions in Brazil and Paraguay target major soybean diseases, including Asian soybean rust, target spot and Cercospora leaf blight. The company said Promisin’s peptide-based mode of action is intended to support resistance management by disrupting fungal cell membranes and can be used as a rotation partner or in tank mixes with other crop protection products.

Micropep said Promisin was developed to address increasing fungicide resistance, changing regulatory requirements and demand for biological crop protection products. The company also highlighted its broad-spectrum activity, compatibility with existing spray programs, favourable safety profile and cost structure designed for large-scale row crop production.

“Promisin shows that peptide-based solutions can deliver the performance, scalability, and economics required for broad agricultural adoption, opening the door to a new generation of products for growers worldwide,” said Georg Goeres, chief executive officer of Micropep.